|Anadrol: Profile, General Information, Stacking and Use
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Pharmaceutical Name: Oxymetholone
Chemical structure: 17 beta-hydroxy-2-hydroxymethylene-17alpha-methyl-5 alpha-androstan-3-one
Molecular weight of base: 332.482
Anadrol is the brand name of oxymetholone. It is a very strong oral androgenic steroid. It acts rapidly and causes exceptional increases in muscle mass. Using it, a user may experience gains of up to 10 pounds in a period of time as short as two weeks. This is due to a low to moderate androgenic effect combined with a very powerful anabolic effect. As a result of this potential rapid gain in mass, gains can be excepted to be accompanied by increased levels of water retention. Anadrol showed potential in treating cases of severe anemia due to its ability to increase red blood cell production. This is a characteristic of most anabolic-androgenic steroids. Studies have shown that oxymetholone demonstrate anti-wasting properties which can be used in cases of AIDS wasting. This should be no surprise, as many steroids have this property.
The estrogenic effects of anadrol may not be mediated by estrogen, but by oxymetholone itself activating the estrogen receptor. Little to no aromatization occurs off oxymetholone. Studies have shown that the progestational effects of oxymetholone and methandrostenolone were not at all comparable to those of testosterone or nandrolone. This rules out the possibility of progestagenic activity and aromatization. This only leaves the oxymetholone engaging in a structure with the estrogen receptor itself. Oxymetholone has an A-Ring similar to that of estradiol, so this would explain the related aromatizing activity. Progesterone acts as an estrogen agonist, and as a result, requires circulating estrogen to negotiate related levels of water build-up.
Anadrol is considered by many users to the the single most potent steroid. Results are said to be extremely dramatic - as mentioned above, users may experience gains of up to 10 pounds in a period of time as short as two weeks. Extreme increases in mass - as much as 20-30 pounds for the novice user, may be seen in periods of time as little as six weeks, and on doses of anadrol as low as 50-100 mg. Although water retention is a big part of the picture when anadrol is used, this still adds to the overall size gains experience by the user as well as those in strength. The user should be aware that such dramatic gains in mass may put high levels of stress on the connective tissues. It is possible to gain mass too quickly.
Water rentention is beneficial for the user. Water retention results in lubrication of the joints, which can make training more comfortable and pain free - even while working out with extremely heavy weights which will come with the gains from anadrol use. More nutrients are also retained inside the cell, which will hopefully result in permanent growth in muscle tissue. With the increase of estrogen, comes the increased risk of estrogen related side effects such as gyno. As a result, the anadrol using athlete should be sure to have ancillary drugs such as anti-estrogens on hand during cycle. Nolvadex or its weaker counterpart, clomid should be kept on hand and administered if signs or symptoms of gyno begin. It should be noted that gains attained from anadrol are largely estrogen mediated, so reducing levels of circulating estrogen may reduce results as well.
Blood volume is increased when using anadrol due to the fact that it is a mild androgen as well as a potent estrogen. Androgens raise the red blood cells to improve aerobic performance. Estrogens increase the level of white blood cells in an attempt to stimulate the immunity. The overall result of this is dramatically improved pumps for the user.
Since anadrol is the strongest steroid, its use should be strictly regulated and brief in duration. The reason for this is because it is most hazardous to your health and potential for problems arise when it is used in high doses or over extended periods of time.
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Steroid related side effects such as acne, vulgaris, benign prostate hypertrophy, gynecomastia and androgenetic alopecia are possible when using anadrol. Of more important concern lies in the fact that anadrol is a 17-alpha-akylated steroid in the same class as dianabol and winstrol. It has notable hepatoxicity, greater than either of the other two drugs mentioned. Raises in liver transaminase enzyme count is inevitable with its use. There are also intrinsic side effects related to this steroid - those include headaches, insomnia, diarrhea, stomach aches, nausea, and vomiting. Although these side effects are normally noted when anadrol is used in high doses or over extended periods of time, it should be noted that the potential exists for these side effects to appear regardless of the dose.
STACKING AND USE
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Since anadrol is a 17-AA steroid, it should not be used for longer than six weeks at a time, and you should consult with your physician prior to its use to check your liver values before as well as post cycle. Good results can be obtained with a single daily dose - this is due to its relatively long activity and poor affinity. A single dose of 50-100 mg every day is recommended. Since it acts rapidly, anadrol is used to jump start cycles when stacked with a longer acting single ester testosterone. In this sense, it is much the same as dianabol.
CHEMICAL MUSCLE ENHANCEMENT
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